SCHEMBL9339604

SCHEMBL9339604

[CH2][Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
TSHR P16473 4/20 0.35
ACHE P22303 2/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
MAPT P10636 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852151 0.81 ESR1 (0.44) ESR1ESR2NR1H2NR1H3TSHR
Ethylene SCHEMBL25342007 0.75 ESR1 (0.44) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL439491 0.73 ESR1 (0.36) ESR1ESR2TSHRACHELMNA
SCHEMBL2169977 0.73 ESR1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL92396 0.73 ESR1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL239179 0.73 ESR1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL439492 0.73 ESR1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL63526 0.73 ESR1 (0.70) ESR1ESR2NR1H2NR1H3TSHR
Formaldehyde SCHEMBL28845505 0.73 ESR1 (0.42) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL7768857 0.71 ESR1 (0.46) ESR1ESR2NR1H2NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379173-B1 Energy beam lithography resist materials FUJITSU LTD (JP) 1994-06-08 EP claimed
EP-3604362-B1 MULTI-COMPONENT POLAR OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME JAPAN POLYETHYLENE CORP (JP) 2023-08-02 EP disclosed
US-20230132484-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-04 US disclosed
US-20230129371-A1 STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-27 US disclosed
EP-4126992-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS Dow Global Technologies LLC (US) 2023-02-08 EP disclosed
EP-4126991-A1 STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS Dow Global Technologies LLC (US) 2023-02-08 EP disclosed
US-11168166-B2 Multi-component polar olefin copolymer and method for producing the same JAPAN POLYETHYLENE CORPORATION (JP) 2021-11-09 US disclosed
WO-2021202722-A1 STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-07 WO disclosed
WO-2021202714-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-07 WO disclosed
US-10975182-B2 Polar group-containing olefin copolymer, multinary polar olefin copolymer, olefin resin composition, and adhesive material, laminate, and other application products using same JAPAN POLYETHYLENE CORPORATION (JP) 2021-04-13 US disclosed
EP-2573854-B1 NON-AQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY MITSUI CHEMICALS INC (JP) 2017-01-04 EP disclosed
CN-102893443-B Nonaqueous electrolyte solution containing silyl ester group-containing phosphonic acid derivative, and lithium secondary battery MITSUI CHEMICALS, INC. (JP) 2015-12-16 CN disclosed
US-8993158-B2 Nonaqueous electrolyte solution containing silyl ester group-containing phosphonic acid derivative, and lithium secondary battery MITSUI CHEMICALS, INC. (JP) 2015-03-31 US disclosed
US-20150004344-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER, MULTINARY POLAR OLEFIN COPOLYMER, OLEFIN RESIN COMPOSITION, AND ADHESIVE MATERIAL, LAMINATE, AND OTHER APPLICATION PRODUCTS USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2015-01-01 US disclosed
EP-2796480-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER, MULTINARY POLAR OLEFIN COPOLYMER, OLEFIN RESIN COMPOSITION, AND ADHESIVE MATERIAL, LAMINATE, AND OTHER APPLICATION PRODUCTS USING SAME Japan Polyethylene Corporation (JP) 2014-10-29 EP disclosed
EP-2573854-A1 NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY Mitsui Chemicals, Inc. (JP) 2013-03-27 EP disclosed
US-20130071732-A1 NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY MITSUI CHEMICALS, INC. (JP) 2013-03-21 US disclosed
EP-0239170-A1 Stabilized lactam polymerization solutions DSM RIM NYLON V.O.F (NL) 1987-09-30 EP disclosed
US-4694039-A Stabilized lactam polymerization solutions DSM RIM NYLON V.O.F. (NL) 1987-09-15 US disclosed
US-4672085-A LACTAM SUBSTITUTED POLYBUTADIENE INITIATOR,TRISUBTITED UREA STABILIZER;NYLON BLOCK COPOLYMERS DSM RIM NYLON VOF (NL) 1987-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130071732-A1 NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY PHOSPHO1, PSPH, SGK2 ESR1 1411/4885ESR2 3007/4885NR1H2 3747/4885
US-20230129371-A1 STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS PCNA, NIT2, MCM7 ESR1 321/4885ESR2 676/4885NR1H2 3716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.