Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339604 | 0.81 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| Water SCHEMBL28099446 | 0.78 | ESR1 (0.67) | ESR1ESR2NR1H2NR1H3TSHR | |
| Ethylene SCHEMBL25342007 | 0.75 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL439491 | 0.73 | ESR1 (0.36) | ESR1ESR2TSHRLMNAALOX12 | |
| SCHEMBL2169977 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL92396 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL239179 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL63526 | 0.73 | ESR1 (0.70) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL439492 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL2143198 | 0.73 | ACHE (0.47) | TSHRLMNAALOX12ACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470123-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIALS, RELATED COMPOSITIONS AND METHODS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-10-27 | — | — | EP | claimed |
| US-20040067994-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIALS, AND RELATED COMPOSITIONS AND METHODS | PAGET STEVEN D (US) | 2004-04-08 | — | — | US | claimed |
| US-6608081-B2 | Treating pneumonia | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-08-19 | — | — | US | claimed |
| WO-2003064415-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIAL, RELATED COMPOSITIONS AND METHODS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-08-07 | — | — | WO | claimed |
| US-20020161029-A1 | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-10-31 | — | — | US | claimed |
| EP-0437784-B1 | Imidazolidine derivatives, process for producing the same and pesticides containing the same | ISHIHARA SANGYO KAISHA (JP) | 1996-04-17 | — | — | EP | claimed |
| EP-0458061-B1 | Agent for preserving wood and wooden materials | DESOWAG MATERIALSCHUTZ GMBH (DE) | 1995-10-11 | — | — | EP | claimed |
| EP-0458060-B1 | Agent for preserving wood and wooden materials | DESOWAG MATERIALSCHUTZ GMBH (DE) | 1995-10-11 | — | — | EP | claimed |
| US-5256674-A | Inecticides, miticides, nematocides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1993-10-26 | — | — | US | claimed |
| EP-0214842-B1 | ORGANOTIN COMPOUNDS AND PESTICIDES CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1992-02-05 | — | — | EP | claimed |
| EP-0437784-A1 | Imidazolidine derivatives, process for producing the same and pesticides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-07-24 | — | — | EP | claimed |
| US-4935408-A | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | claimed |
| JP-1170620-A | — | — | None | — | — | JP | disclosed |
| EP-3604362-B1 | MULTI-COMPONENT POLAR OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME | JAPAN POLYETHYLENE CORP (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-20230132484-A1 | STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-05-04 | — | — | US | disclosed |
| US-4774235-A | MITICIDES | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| US-4237137-A | Sila-substituted 1,4-dihydropyridine derivatives and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161029-A1 | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods | OXA1L, NDUFS3, CYCS | ESR1 2909/4885ESR2 1991/4885NR1H2 2006/4885 |
| US-20040067994-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIALS, AND RELATED COMPOSITIONS AND METHODS | OXA1L, NDUFS3, CYCS | ESR1 2909/4885ESR2 1991/4885NR1H2 2006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.