Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935243 | 0.82 | EPHX1 (0.44) | EPHX1LMNAHTT | |
| SCHEMBL934143 | 0.79 | EPHX1 (0.45) | EPHX2EPHX1 | |
| SCHEMBL8245050 | 0.78 | PTPRZ1 (0.55) | PTPRZ1SLC6A4PTPN1EPHX2NR1H4 | |
| SCHEMBL15881064 | 0.76 | TRPA1 (0.52) | TDP1EPHX1HTT | |
| SCHEMBL20166265 | 0.76 | GRB2 (0.60) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL12439873 | 0.76 | GRB2 (0.60) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL934005 | 0.75 | EPHX1 (0.60) | PTPN1EPHX2NR1H4EPHX1 | |
| Hydrochloric Acid SCHEMBL5795299 | 0.75 | TRPA1 (0.50) | TDP1EPHX1HTT | |
| SCHEMBL9108524 | 0.75 | PTPRZ1 (0.61) | PTPRZ1PTPN1KIF11EPHX2NR1H4 | |
| SCHEMBL27465180 | 0.74 | CYP19A1 (0.40) | PTPRZ1SLC6A4PTPN1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |