Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394820 | 0.79 | — | — | |
| SCHEMBL10073990 | 0.77 | ELOVL1 (0.36) | EGFRALDH1A1 | |
| Water SCHEMBL9340526 | 0.76 | — | — | |
| Water SCHEMBL9340500 | 0.76 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL19597433 | 0.67 | — | — | |
| SCHEMBL8102492 | 0.67 | MEN1 (0.41) | ALDH1A1 | |
| Ether SCHEMBL6396881 | 0.67 | MAPT (0.46) | ALDH1A1 | |
| Ether SCHEMBL11883416 | 0.66 | — | — | |
| Ether SCHEMBL5326237 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| Ether SCHEMBL4564573 | 0.63 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | claimed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |