Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961831 | 0.83 | HTR2C (0.50) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7934151 | 0.83 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1POLBHPGDNCF1 | |
| SCHEMBL1547577 | 0.83 | L3MBTL1 (0.53) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7922045 | 0.82 | L3MBTL1 (0.40) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL878692 | 0.81 | FAAH (0.53) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14402360 | 0.81 | HPGD (0.47) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2556120 | 0.80 | L3MBTL1 (0.41) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6898105 | 0.80 | L3MBTL1 (0.66) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12668117 | 0.79 | FFAR1 (0.43) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27724471 | 0.79 | LMNA (0.43) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401167-B1 | Process for the preparation of titanocenes with o,o'-difluoro ligands | CIBA GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| US-5075467-A | Reacting organotitanium halide with lithium amide | CIBA-GEIGY CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0401167-A2 | Process for the preparation of titanocenes with o,o'-difluoro ligands | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |