Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618406 | 0.85 | TSHR (0.45) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL29514652 | 0.76 | TSHR (0.67) | TSHRSRD5A2KMOMAPTKDM4E | |
| SCHEMBL110094 | 0.76 | TSHR (0.67) | TSHRSRD5A2KMOMAPTKDM4E | |
| SCHEMBL7608864 | 0.73 | TSHR (0.47) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL3566736 | 0.72 | TSHR (0.50) | TSHRALDH1A1SRD5A2KMOMAPT | |
| SCHEMBL101687 | 0.72 | TSHR (0.45) | TSHRALDH1A1SRD5A2KMOMAPT | |
| SCHEMBL29440655 | 0.72 | ALDH1A1 (0.40) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL75886 | 0.72 | ALDH1A1 (0.40) | TSHRALDH1A1TP53CES2CES1 | |
| SCHEMBL11806931 | 0.71 | TSHR (0.43) | TSHRALDH1A1SRD5A2KMOMAPT | |
| SCHEMBL2964948 | 0.71 | TSHR (0.43) | TSHRALDH1A1SRD5A2KMOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448657-A2 | IMPROVED HYBRID TFC RO MEMBRANES WITH NITROGEN ADDITIVES | NanoH2O Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011008549-A2 | IMPROVED HYBRID TFC RO MEMBRANES WITH NITROGEN ADDITIVES | NanoH2O Inc. (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2010123518-A1 | IMPROVED TFC MEMBERANES WITH NANOPARTICLES AND OTHER ADDITIVES | NANOH2O, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010120327-A1 | IMPROVED TFC MEMBRANES WITH HYDROLYZED AND OTHER ADDITIVES | NANOH2O, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010120326-A1 | IMPROVED TFC MEMBRANES WITH HYDROLIZED ADDITIVES | NANOH2O, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010120325-A1 | IMPROVED TFC MEMBRANES WITH ALKALINE EARTH METAL AND OTHER ADDITIVES | NANOH2O, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| US-6444091-B1 | MIXING PULPS WITH POLYAMIDES OR IN COMBINATION WITH COAGULANTS, FLOCCULANTS AND/OR PARTICLES; EFFICIENCY | NALCO CHEMICAL COMPANY | 2002-09-03 | — | — | US | disclosed |