Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092290 | 0.75 | CA2 (0.37) | GAALMNAALDH1A1CA12CA1 | |
| SCHEMBL12315839 | 0.75 | CA2 (0.37) | GAALMNAALDH1A1CA12CA1 | |
| SCHEMBL1558186 | 0.74 | ALDH1A1 (0.36) | GAALMNAALDH1A1CA1CA2 | |
| SCHEMBL3582574 | 0.74 | ALDH1A1 (0.36) | GAALMNAALDH1A1CA1CA2 | |
| SCHEMBL11269784 | 0.65 | LMNA (0.68) | LMNACA12CA1CA2CA7 | |
| SCHEMBL11535854 | 0.64 | LMNA (0.74) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL11261499 | 0.63 | CA12 (0.45) | LMNACRBNCA12CA1CA2 | |
| SCHEMBL9596856 | 0.62 | GAA (0.31) | GAALMNAALDH1A1 | |
| SCHEMBL11532812 | 0.62 | LMNA (0.46) | LMNACRBNCA12CA1CA2 | |
| SCHEMBL11532808 | 0.62 | LMNA (0.46) | LMNACRBNCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308842-A | Ocular hypotensive agents; glaucoma | MERCK & CO., INC. (US) | 1994-05-03 | — | — | US | disclosed |