Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079379 | 0.73 | KMT2A (0.56) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL11040285 | 0.72 | ALDH1A1 (0.48) | KMT2AMAPTHTTLMNAALDH1A1 | |
| SCHEMBL11061920 | 0.70 | PTGES (0.66) | KMT2AMAPTTSHRHTTRAB9A | |
| SCHEMBL9345348 | 0.70 | ADORA1 (0.50) | MAPK10ADORA1PTGS2 | |
| SCHEMBL11078932 | 0.69 | KMT2A (0.67) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL10999778 | 0.68 | KMT2A (0.60) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL11502725 | 0.67 | MAPK14 (0.55) | — | |
| SCHEMBL10909971 | 0.67 | OPRD1 (0.45) | MAPTALDH1A1NT5EPTGS2KDM4E | |
| SCHEMBL9695434 | 0.66 | KMT2A (0.66) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL10998119 | 0.66 | KMT2A (0.61) | KMT2AMAPTHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | claimed |
| EP-0361185-B1 | 2-halogenomethylthio-substituted pyrimidine derivatives | BAYER AG (DE) | 1994-06-22 | — | — | EP | disclosed |
| US-4978382-A | Insecticides, miticides, nematocides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-18 | — | — | US | disclosed |
| EP-0361185-A2 | 2-halogenomethylthio-substituted pyrimidine derivatives | BAYER AG (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | disclosed |