SCHEMBL934322

SCHEMBL934322

CCOC(=O)C(C)CCO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 2/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TRPA1 O75762 1/20 0.36
CPB2 Q96IY4 1/20 0.35
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18270548 1.00 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL18270579 1.00 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL14616914 0.87 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL4922700 0.86 CYP4F2 (0.40) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL18098084 0.85 CYP4F2 (0.43) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL29082552 0.83 CHRNB2 (0.32) ALDH1A1KMT2AMEN1GABRPGABRD
SCHEMBL8245481 0.83 SMN1; SMN2 (0.45) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL13483255 0.83 SMN1; SMN2 (0.45) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL28182020 0.83 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4
SCHEMBL113543 0.83 SMN1; SMN2 (0.45) ALDH1A1LMNAHSD17B10CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908825-A Method for synthesizing 3-hydroxy ethyl butyrate 东莞理工学院 2024-11-08 CN disclosed
CN-105392777-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2020-09-22 CN disclosed
EP-3013796-B9 BIARYL DERIVATIVES AS GPR120 AGONISTS LG CHEMICAL LTD (KR) 2020-07-01 EP disclosed
EP-3628661-A1 BIARYL DERIVATIVES AS GPR120 AGONISTS LG CHEM, LTD. (KR) 2020-04-01 EP disclosed
US-10307434-B2 Nucleic acid prodrugs and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2019-06-04 US disclosed
CN-109688813-A Flying pest attractant 理研香料控股株式会社 2019-04-26 CN disclosed
US-10221138-B2 Biaryl derivatives as GPR120 agonists LG CHEM, LTD. (KR) 2019-03-05 US disclosed
CN-109310085-A Flying pest attractant 理研香料控股株式会社 2019-02-05 CN disclosed
US-9744183-B2 Nucleic acid prodrugs and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2017-08-29 US disclosed
US-20160347784-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES PTE. LTD. (SG) 2016-12-01 US disclosed
EP-1335903-A1 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2003-08-20 EP disclosed
EP-1301483-A1 1-ARYL-4-ALKYL HALIDE-2(1H)-PYRIDONES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-04-16 EP disclosed
EP-1289970-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-03-12 EP disclosed
EP-1244635-A2 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLE BASF AKTIENGESELLSCHAFT (DE) 2002-10-02 EP disclosed
WO-2002042275-A1 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2002-05-30 WO disclosed
WO-2002006233-A1 1-ARYL-4-ALKYL HALIDE-2(1H)-PYRIDONES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-24 WO disclosed
WO-2001087863-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-22 WO disclosed
WO-2001049668-A2 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLES AND USE THEREOF AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-07-12 WO disclosed
US-4929754-A CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS DR. KARL THOMAE GMBH (DE) 1990-05-29 US disclosed
US-4820705-A ANTITUMOR, CARDIOVASCULR DISORDERS DR. KARL THOMAE GMBH (DE) 1989-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160347784-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF PNP, RNGTT, TYMP ALDH1A1 1085/4885LMNA 904/4885HSD17B10 1879/4885
US-10221138-B2 Biaryl derivatives as GPR120 agonists GPR119, GLP1R, GIPR ALDH1A1 2063/4885LMNA 1883/4885HSD17B10 1051/4885
US-10307434-B2 Nucleic acid prodrugs and methods of use thereof PNP, RNGTT, NSUN2 ALDH1A1 899/4885LMNA 723/4885HSD17B10 1839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.