Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344314 | 0.88 | MMP2 (0.34) | MMP2MMP9 | |
| SCHEMBL9349025 | 0.81 | MMP2 (0.36) | MMP2MMP9 | |
| SCHEMBL9348788 | 0.79 | MMP2 (0.34) | MMP2MMP9 | |
| SCHEMBL9345631 | 0.75 | MMP2 (0.34) | MMP2MMP9 | |
| SCHEMBL9344161 | 0.74 | ITGB3 (0.43) | — | |
| SCHEMBL14394506 | 0.73 | GNAI3 (0.46) | — | |
| SCHEMBL9344174 | 0.72 | MMP2 (0.36) | MMP2MMP9 | |
| SCHEMBL9330359 | 0.72 | MMP2 (0.38) | MMP2MMP9 | |
| SCHEMBL2803178 | 0.72 | MMP2 (0.38) | MMP2MMP9 | |
| SCHEMBL9330370 | 0.71 | MMP2 (0.41) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |