Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.84 |
| ▸ | HPGD | P15428 | 5/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 2/20 | 0.84 |
| ▸ | HTT | P42858 | 2/20 | 0.84 |
| ▸ | BRD4 | O60885 | 1/20 | 0.84 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.84 |
| ▸ | MEN1 | O00255 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | RAD52 | P43351 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norfloxacin SCHEMBL28226779 | 0.92 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL2221304 | 0.91 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL3473 | 0.91 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL27395494 | 0.91 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9634547 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL10886039 | 0.90 | ALDH1A1 (0.98) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL10911469 | 0.90 | ALDH1A1 (0.98) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL9788079 | 0.90 | ALDH1A1 (0.98) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL11524201 | 0.90 | ALDH1A1 (0.98) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Norfloxacin SCHEMBL3147077 | 0.90 | ALDH1A1 (0.98) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-8962786-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LTD (AU) | 2015-02-24 | — | — | US | disclosed |
| US-20120046246-A1 | METHODS FOR TREATING OSTEOCLAST-RELATED DISEASE, COMPOUNDS AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746116-B2 | Antibiotic resistance breakers | ABCC1, ARL1, AKR1C3 | KDM4E 3599/4885ALDH1A1 481/4885HPGD 3875/4885 |
| US-20120046246-A1 | METHODS FOR TREATING OSTEOCLAST-RELATED DISEASE, COMPOUNDS AND COMPOSITIONS THEREOF | CTSB, SOST, CTSG | KDM4E 1873/4885ALDH1A1 2363/4885HPGD 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.