Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.56 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601206 | 1.00 | MAPT (0.67) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL2208983 | 0.93 | MAPT (0.74) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL935705 | 0.85 | MAPT (0.74) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL20162268 | 0.85 | ALDH1A1 (0.57) | MAPTGLO1ABL1ALDH1A1HPGD | |
| SCHEMBL2903666 | 0.84 | PTP4A3 (0.57) | MAPTGLO1ABL1ALDH1A1TDP1 | |
| SCHEMBL27587573 | 0.83 | ALDH1A1 (0.70) | MAPTALDH1A1CYP1A2EGFRCA12 | |
| SCHEMBL20162254 | 0.83 | MAPT (0.46) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL16307895 | 0.82 | MAPT (0.74) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL7793570 | 0.82 | MAPT (0.51) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL8331758 | 0.81 | HPGD (0.49) | MAPTALDH1A1TDP1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | claimed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | claimed |
| WO-2017008877-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | WO | claimed |
| EP-1952843-B1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | claimed |
| US-20210161783-A1 | USE OF SPECIFIC BENZYLIDENE MALONATES FOR PROTECTING THE SKIN FROM CHEMICALLY INDUCED STRESS | MERCK PATENT GMBH (DE) | 2021-06-03 | — | — | US | disclosed |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017008877-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | WO | disclosed |
| EP-2931714-B1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-9458142-B2 | Substituted quinones or analogues as colouring agents | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| WO-2016142026-A1 | FLUORINE SURFACTANTS IN EMULSIONS | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | WO | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20130059924-A1 | PHOTOSTABILISERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| US-20130058879-A1 | TRIAZINES AS REACTION ACCELERATORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| WO-2012107158-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012065685-A1 | ASCORBIC ACID DERIVATIVES AS OXIDATION DYE COMPONENTS | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012028245-A1 | DYE-ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2011141111-A2 | TRIAZINES AS REACTION ACCELERATORS | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141110-A2 | PHOTO-STABILIZING AGENTS | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011006566-A2 | MONOMETHOXY-HYDROXY-BENZYLMALONATES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | KRT18, IK, SDHA | MAPT 411/4885GLO1 825/4885ABL1 928/4885 |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | MAPT 1864/4885GLO1 255/4885ABL1 4102/4885 |
| US-20130059924-A1 | PHOTOSTABILISERS | ALDH1A1, ALDH18A1, ALDH1A2 | MAPT 362/4885GLO1 221/4885ABL1 2185/4885 |
| US-20130058879-A1 | TRIAZINES AS REACTION ACCELERATORS | TYR, NAT1, TERT | MAPT 3734/4885GLO1 2921/4885ABL1 421/4885 |
| US-20210161783-A1 | USE OF SPECIFIC BENZYLIDENE MALONATES FOR PROTECTING THE SKIN FROM CHEMICALLY INDUCED STRESS | MAL2, GAA, ME2 | MAPT 2297/4885GLO1 512/4885ABL1 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.