Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.41 |
| ▸ | PTP4A2 | Q12974 | 2/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211610 | 0.94 | KDM4E (0.56) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL2905466 | 0.90 | ALDH1A1 (0.50) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL934472 | 0.86 | MAPT (0.59) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL2212255 | 0.86 | KDM4E (0.48) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL2269143 | 0.85 | KMT2A (0.47) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL23407467 | 0.85 | ALOX5 (0.62) | KMT2APKMKDM4EGAAALOX5 | |
| SCHEMBL23407458 | 0.82 | ALOX5 (0.52) | KMT2APKMKDM4EALDH1A1ALOX5 | |
| SCHEMBL2897877 | 0.81 | KMT2A (0.57) | KMT2APKMKDM4EALDH1A1GAA | |
| SCHEMBL23407460 | 0.81 | ALOX5 (0.51) | KMT2AKDM4EALDH1A1ALOX5CYP1A2 | |
| SCHEMBL2216850 | 0.80 | MAPT (0.66) | KMT2APKMKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12453682-B2 | Composition comprising at least 5% by weight of titanium oxides, an α-cyanodiphenylacrylate derivative and a 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative | L'ORÉAL (FR) | 2025-10-28 | — | — | US | claimed |
| US-20230044544-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN a-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2023-02-09 | — | — | US | claimed |
| EP-4076677-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2022-10-26 | — | — | EP | claimed |
| WO-2021122039-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2021-06-24 | — | — | WO | claimed |
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | claimed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| CN-1798538-A | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2006-07-05 | — | — | CN | claimed |
| US-12453682-B2 | Composition comprising at least 5% by weight of titanium oxides, an α-cyanodiphenylacrylate derivative and a 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative | L'ORÉAL (FR) | 2025-10-28 | — | — | US | disclosed |
| US-20230044544-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN a-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2023-02-09 | — | — | US | disclosed |
| EP-4076677-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021122039-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | L'OREAL (FR) | 2021-06-24 | — | — | WO | disclosed |
| CN-104869974-A | Compositions and/or articles with improved solubility of solid active substances | PROCTER & GAMBLE | 2015-08-26 | — | — | CN | disclosed |
| CN-104302268-A | Personal care compositions with improved solubility of a solid cosmetic active substance | PROCTER & GAMBLE | 2015-01-21 | — | — | CN | disclosed |
| CN-104144676-A | Sunscreen compositions comprising UV composites | PROCTER & GAMBLE | 2014-11-12 | — | — | CN | disclosed |
| CN-104039396-A | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING | PROCTER & GAMBLE | 2014-09-10 | — | — | CN | disclosed |
| CN-103930167-A | Personal care compositions comprising a di-amido gellant and methods of using | PROCTER & GAMBLE | 2014-07-16 | — | — | CN | disclosed |
| CN-103857376-A | Personal care compositions with improved solubility of a solid UV active | PROCTER & GAMBLE | 2014-06-11 | — | — | CN | disclosed |
| CN-103619308-A | Personal care compositions comprising shaped abrasive particles | PROCTER & GAMBLE | 2014-03-05 | — | — | CN | disclosed |
| CN-1798538-A | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2006-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044544-A1 | COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN a-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE | HAAO, HAO2, HPD | KMT2A 1848/4885PKM 2334/4885KDM4E 470/4885 |
| US-12453682-B2 | Composition comprising at least 5% by weight of titanium oxides, an α-cyanodiphenylacrylate derivative and a 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative | HAAO, HPD, P4HA1 | KMT2A 2101/4885PKM 2271/4885KDM4E 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.