Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345620 | 0.85 | P2RX7 (0.51) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| SCHEMBL9344875 | 0.84 | P2RX7 (0.56) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| SCHEMBL9345720 | 0.84 | HTR1A (0.40) | HRH2HRH1HRH3HTR1AHTR7 | |
| SCHEMBL9349827 | 0.84 | HTR1A (0.51) | HRH1HRH3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9345702 | 0.84 | P2RX7 (0.52) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| Hydrochloric Acid SCHEMBL9345669 | 0.83 | ALDH1A1 (0.39) | LMNAHRH1HRH3HTR1ASMN1; SMN2 | |
| SCHEMBL9345613 | 0.83 | P2RX7 (0.49) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| Hydrochloric Acid SCHEMBL9345690 | 0.82 | P2RX7 (0.50) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| SCHEMBL9477054 | 0.80 | ADRA1A (0.58) | P2RX7KCNA3PRKD3PRKCGPRKCB | |
| SCHEMBL9346876 | 0.79 | HRH3 (0.39) | LMNAHRH2HRH1HRH3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |