Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9345669 | 0.89 | ALDH1A1 (0.39) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9349827 | 0.86 | HTR1A (0.51) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9345607 | 0.84 | HTR7 (0.46) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9344869 | 0.84 | P2RX7 (0.48) | HTR1AHTR7HRH1HRH3SMN1; SMN2 | |
| SCHEMBL9349805 | 0.83 | SMN1; SMN2 (0.41) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9349897 | 0.81 | SMN1; SMN2 (0.39) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9346876 | 0.81 | HRH3 (0.39) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9345642 | 0.80 | DRD2 (0.40) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9346897 | 0.79 | HTR1A (0.39) | HTR1AHTR7DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9349905 | 0.76 | HTR1A (0.38) | HTR1AHTR7DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |