Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696537 | 1.00 | MAPT (0.41) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9696544 | 0.93 | ALOX15 (0.43) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9696046 | 0.93 | ALOX15 (0.43) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9696523 | 0.93 | MAPT (0.42) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9695986 | 0.90 | MAPT (0.43) | MAPTHPGDALDH1A1KMT2ANPC1 | |
| SCHEMBL9696955 | 0.86 | MAPT (0.44) | MAPTHPGDALDH1A1KMT2ANPC1 | |
| SCHEMBL9696975 | 0.86 | ADRB2 (0.41) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9696527 | 0.85 | ALOX15 (0.43) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9348914 | 0.84 | MAPT (0.40) | MAPTALOX15HPGDALDH1A1ADRB2 | |
| SCHEMBL9344930 | 0.84 | MAPT (0.40) | MAPTALOX15HPGDALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |