Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 9/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345661 | 0.90 | CARM1 (0.42) | HTR4ADRA2CHTR1DADRA1BHTR2B | |
| SCHEMBL4231380 | 0.78 | CARM1 (0.41) | HTR4ADRA2CHTR1DADRA1BHTR2B | |
| SCHEMBL9345688 | 0.76 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| Oxalic Acid SCHEMBL9344962 | 0.75 | CHRM3 (0.41) | CHRM3CHRM1CARM1PRMT6 | |
| SCHEMBL9332530 | 0.74 | KEAP1 (0.47) | CHRM3CHRM1CARM1PRMT6CYP2D6 | |
| SCHEMBL9333108 | 0.74 | ACHE (0.40) | HTR4 | |
| SCHEMBL9343697 | 0.74 | NCF1 (0.54) | CHRM1CARM1PRMT6CYP2D6 | |
| SCHEMBL9349148 | 0.73 | PRMT3 (0.41) | CHRM3CHRM4CHRM1CARM1PRMT6 | |
| SCHEMBL11205736 | 0.72 | KEAP1 (0.48) | CHRM1CARM1PRMT6CYP2D6 | |
| SCHEMBL22691908 | 0.72 | KEAP1 (0.48) | CHRM1CARM1PRMT6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |