Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 9/20 | 0.33 |
| ▸ | CA2 | P00918 | 9/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346495 | 0.81 | ADK (0.39) | CA1CA2CA12CA9 | |
| SCHEMBL6029011 | 0.73 | HIF1A (0.42) | TSHRPNP | |
| SCHEMBL11120862 | 0.73 | HIF1A (0.42) | TSHRPNP | |
| SCHEMBL5488865 | 0.73 | HIF1A (0.42) | TSHRPNP | |
| SCHEMBL9346485 | 0.68 | ADK (0.42) | CA1CA2CA12CA9TSHR | |
| SCHEMBL7764674 | 0.64 | ADK (0.54) | CA1CA2CA12CA9TSHR | |
| SCHEMBL1701475 | 0.62 | MMP12 (0.41) | EGLN1 | |
| SCHEMBL9805221 | 0.62 | ADK (0.51) | CA1CA2TSHRPNP | |
| SCHEMBL5063261 | 0.62 | TSHR (0.43) | CA1CA2CA12CA9TSHR | |
| Ribose (Furanose) SCHEMBL1527280 | 0.61 | ATM (0.43) | TSHRPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |