Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 11/20 | 0.36 |
| ▸ | CA2 | P00918 | 11/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350448 | 0.84 | DNPH1 (0.41) | ADORA1SMN1; SMN2 | |
| SCHEMBL7764674 | 0.76 | ADK (0.54) | ADKCA1CA2CA9CA12 | |
| SCHEMBL9346495 | 0.74 | ADK (0.39) | ADKCA1CA2CA9CA12 | |
| Adenine SCHEMBL14636444 | 0.72 | HIF1A (0.49) | ADKDPP4HIF1AMEN1SLC28A1 | |
| SCHEMBL9350437 | 0.72 | STING1 (0.46) | KMT2A | |
| Ribose (Furanose) SCHEMBL2505730 | 0.71 | ADK (0.40) | ADKDPP4HIF1AMEN1SLC28A1 | |
| Ribose (Furanose) SCHEMBL4542668 | 0.71 | ADK (0.40) | ADKDPP4HIF1AMEN1SLC28A1 | |
| SCHEMBL9346501 | 0.70 | HIF1A (0.35) | HIF1AMEN1STAT6KMT2ASMN1; SMN2 | |
| Adenine SCHEMBL9007542 | 0.68 | FBP1 (0.46) | ADKDPP4HIF1AMEN1SLC28A1 | |
| SCHEMBL9805221 | 0.67 | ADK (0.51) | ADKCA1CA2HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0353268-A4 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RES INST (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0353268-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RESEARCH INST (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989005817-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |