Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68930 | 0.85 | CYP4Z1 (0.57) | ALDH1A1TBXAS1MAPTCYP4Z1LIPE | |
| SCHEMBL11847298 | 0.84 | MAPT (0.51) | ALDH1A1TBXAS1MAPTCYP4Z1LIPE | |
| SCHEMBL181473 | 0.84 | HPGD (0.61) | ALDH1A1HPGDTBXAS1MAPTCYP4Z1 | |
| SCHEMBL6781796 | 0.83 | TBXAS1 (0.57) | ALDH1A1HPGDTBXAS1KDM4ESMN1; SMN2 | |
| SCHEMBL8147343 | 0.83 | TBXAS1 (0.57) | ALDH1A1HPGDTBXAS1MAPTCYP4Z1 | |
| SCHEMBL9347360 | 0.83 | KMT2A (0.59) | ALDH1A1HPGDMAPTL3MBTL1GAA | |
| SCHEMBL25242319 | 0.81 | TBXAS1 (0.54) | ALDH1A1HPGDTBXAS1MAPTCYP4Z1 | |
| SCHEMBL12126600 | 0.80 | CYP4Z1 (0.53) | ALDH1A1TBXAS1MAPTCYP4Z1LIPE | |
| SCHEMBL11839196 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTCYP4Z1THRB | |
| SCHEMBL68851 | 0.80 | CYP4Z1 (0.62) | ALDH1A1TBXAS1MAPTCYP4Z1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |