SCHEMBL9348102

SCHEMBL9348102

Cc1c(N)cc(Br)c(O)c1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
PTPN1 P18031 1/20 0.41
CYP3A4 P08684 4/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
GPR35 Q9HC97 1/20 0.39
ALDH1A1 P00352 5/20 0.37
ALOX15 P16050 3/20 0.37
HIF1A Q16665 3/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP1A2 P05177 2/20 0.37
HPGD P15428 2/20 0.37
ALOX12 P18054 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495935 0.82 ALDH1A1 (0.46) CA1CA2PTPN1CYP3A4TSHR
Tribromometacresol SCHEMBL467297 0.78 CA1 (0.52) CA1CA2CA4CA6PTPN1
Tribromometacresol SCHEMBL30255705 0.78 CA1 (0.52) CA1CA2CA4CA6PTPN1
SCHEMBL11131454 0.76 MAPT (0.42) CA1CA2CYP3A4TSHRTDP1
SCHEMBL12192916 0.75 GABRA1 (0.50) CA1CA2CYP3A4TSHRALDH1A1
SCHEMBL9478468 0.71 CA1 (0.35) CA1CA2CA4CA6PTPN1
SCHEMBL17744522 0.70 ALDH1A1 (0.60) CA1CA2CA4CA6CYP3A4
SCHEMBL17744621 0.70 CD44 (0.41) CA1CA2CA4CA6CYP3A4
SCHEMBL9166780 0.70 ALOX5 (0.44) CA1CA2CA4CA6PTPN1
SCHEMBL10824898 0.69 CA1 (0.52) CA1CA2CA4CA6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9745336-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2017-08-29 US disclosed
US-9745336-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2017-08-29 US disclosed
US-20140303003-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof APPLIED BIOSYSTEMS, LLC (US) 2014-10-09 US disclosed
US-20140303003-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof APPLIED BIOSYSTEMS, LLC (US) 2014-10-09 US disclosed
US-8729267-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2014-05-20 US disclosed
US-8729267-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2014-05-20 US disclosed
US-20110250699-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110250699-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof Life Technologies Corporation (US) 2011-10-13 US disclosed
EP-2371927-A1 Fluorescent dye compounds, conjugates and uses thereof Life Technologies Corporation (US) 2011-10-05 EP disclosed
US-7985602-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2011-07-26 US disclosed
EP-0317243-B1 Method and test composition for determination of enzyme activity KYOWA MEDEX CO LTD (JP) 1994-08-31 EP disclosed
US-5223404-A Chromogen, oxidase, compound which releases rate enhancer in presence of peptidase SUNSTAR KABUSHIKI KAISHA (JP) 1993-06-29 US disclosed
EP-0325472-B1 COMPOSITION FOR TESTING PERIODONTAL DISEASES SUNSTAR KABUSHIKI KAISHA (JP) 1993-04-28 EP disclosed
US-5196312-A Coloeimetric analysis, aniline promoter KYOWA MEDEX COMPANY, LTD. (JP) 1993-03-23 US disclosed
EP-0325472-A2 Composition for testing periodontal diseases SUNSTAR KABUSHIKI KAISHA (JP) 1989-07-26 EP disclosed
EP-0317243-A2 Method and test composition for determination of enzyme activity Kyowa Medex Co. Ltd. (JP) 1989-05-24 EP disclosed
US-4752547-A RECORDING LAYER CONTAINS REDUCING AGENT, LEWIS BASE COMPLEX, AND REDUCIBLE DYE FORMING COMPOUND EASTMAN KODAK COMPANY (US) 1988-06-21 US disclosed
US-4727008-A MULTILAYER-IMAGEWISE EXPOSURE TO ELECTRICAL CHARGES OF DIFFERENT POLARITIES TO GIVE DEVELOPABLE IMAGES EASTMAN KODAK COMPANY (US) 1988-02-23 US disclosed
EP-0251761-A2 Multicolor laser recording method and element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-01-07 EP disclosed
US-4684602-A Multicolor laser recording method and element EASTMAN KODAK COMPANY (US) 1987-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110250699-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof GFPT1, SLC46A1, SLC7A5 CA1 2552/4885CA2 3340/4885CA4 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.