Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780176 | 0.78 | THRB (0.32) | THRB | |
| SCHEMBL14670245 | 0.77 | — | — | |
| SCHEMBL9323503 | 0.76 | FAAH (0.32) | LMNATHRBPOLBNPSR1ALDH1A1 | |
| SCHEMBL9017248 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL29544342 | 0.74 | FAAH (0.31) | LMNATHRBPOLBNPSR1 | |
| SCHEMBL14670265 | 0.74 | TSHR (0.36) | LMNAPOLBTSHR | |
| SCHEMBL5947964 | 0.74 | ALDH1A1 (0.36) | LMNATHRBALDH1A1TSHR | |
| SCHEMBL28476006 | 0.73 | ALDH1A1 (0.36) | LMNAALDH1A1TSHR | |
| SCHEMBL9343508 | 0.73 | ALDH1A1 (0.35) | NPSR1ALDH1A1 | |
| SCHEMBL13597406 | 0.73 | THRB (0.38) | LMNATHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362477-A | 19F magnetic resonance imaging agents which include a nitroxide moiety | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-08 | — | — | US | disclosed |