Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL29544342

CCOC(F)(C(=O)O)C(F)(F)F.N

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.31
LMNA P02545 1/20 0.31
CES2 O00748 3/20 0.31
CES1 P23141 5/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HDAC4 P56524 2/20 0.30
HDAC6 Q9UBN7 2/20 0.30
THRB P10828 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323503 0.98 FAAH (0.32) FAAHLMNACES2CES1MEN1
SCHEMBL13597406 0.84 THRB (0.38) FAAHLMNAKMT2APOLBTHRB
Ammonia Solution, Strong SCHEMBL1580153 0.83 LMNA (0.33) LMNACES2
SCHEMBL28101052 0.81 THRB (0.45) KMT2APOLBTHRB
SCHEMBL1784672 0.80 LMNA (0.34) FAAHLMNACES2KMT2A
SCHEMBL236460 0.79 ALOX15 (0.33) FAAHCES2CES1MEN1CYP1A2
Fluoride SCHEMBL9617438 0.78 LMNA (0.33) LMNACES2
Hydrochloric Acid SCHEMBL10522738 0.78 LMNA (0.33) LMNACES2
SCHEMBL13698698 0.77 ALOX15 (0.37) FAAHCES2CES1MEN1CYP1A2
SCHEMBL7262141 0.77 CES2 (0.39) FAAHCES2CES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230383029-A1 PREPARATION METHOD OF PTFE DISPERSION RESIN WITH CORE-SHELL STRUCTURE ZHEJIANG JUSHENG FLUOROCHEMICAL CO., LTD. (CN) 2023-11-30 US disclosed
WO-2022083035-A1 PREPARATION METHOD FOR PTFE DISPERSION RESIN HAVING CORE-SHELL STRUCTURE 浙江巨化技术中心有限公司 2022-04-28 WO disclosed