SCHEMBL9323503

SCHEMBL9323503

CCOC(F)(C(=O)O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.32
LMNA P02545 1/20 0.32
CES2 O00748 3/20 0.31
CES1 P23141 5/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31
POLB P06746 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HDAC4 P56524 2/20 0.31
HDAC6 Q9UBN7 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
NPC1 O15118 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29544342 0.98 FAAH (0.31) FAAHLMNACES2CES1MEN1
SCHEMBL13597406 0.86 THRB (0.38) FAAHLMNAKMT2ATHRBPOLB
SCHEMBL28101052 0.83 THRB (0.45) KMT2ATHRBPOLB
SCHEMBL1784672 0.82 LMNA (0.34) FAAHLMNACES2KMT2AALDH1A1
SCHEMBL236460 0.81 ALOX15 (0.33) FAAHCES2CES1MEN1CYP1A2
Hydrochloric Acid SCHEMBL10522738 0.80 LMNA (0.33) LMNACES2ALDH1A1
Fluoride SCHEMBL9617438 0.80 LMNA (0.33) LMNACES2ALDH1A1
Ammonia Solution, Strong SCHEMBL1580153 0.80 LMNA (0.33) LMNACES2ALDH1A1
SCHEMBL13698698 0.79 ALOX15 (0.37) FAAHCES2CES1MEN1CYP1A2
SCHEMBL7262141 0.79 CES2 (0.39) FAAHCES2CES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116148403-A Micro-extraction method for rapidly extracting short-chain perfluoro and polyfluoroalkyl compound in water sample 上海交通大学 2023-05-23 CN claimed
CN-116148403-A Micro-extraction method for rapidly extracting short-chain perfluoro and polyfluoroalkyl compound in water sample 上海交通大学 2023-05-23 CN disclosed
EP-0583540-A1 Synthesis of desflurane Anaquest, Inc. (US) 1994-02-23 EP disclosed
EP-0331367-B1 Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU (JP) 1993-12-08 EP disclosed
US-5205914-A Synthesis of desflurane ANAQUEST, INC. (US) 1993-04-27 US disclosed
US-5051527-A Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU K.K. (JP) 1991-09-24 US disclosed
EP-0331367-A2 Liquid crystal compounds having fluoroalkyl radical Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-06 EP disclosed
US-4357282-A CONTACTING A FLUORINATED METHYL OR ETHYL EHTER HAVING A METHOXYLATED CARBON ATOM WITH A LEWIS ACID CATALYST ACYLATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-02 US disclosed