Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA6 | P23280 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348405 | 0.83 | CYP3A4 (0.37) | CA1CA2CA4CA6CYP3A4 | |
| SCHEMBL9348570 | 0.80 | CYP3A4 (0.37) | CYP3A4MAPTHTR2ACA9PTGS2 | |
| SCHEMBL9349736 | 0.80 | CYP3A4 (0.37) | CYP3A4MAPTHTR2ACA9PTGS2 | |
| SCHEMBL9352494 | 0.78 | TSHR (0.44) | CA1CA2MAPTHTR2APOLB | |
| SCHEMBL9349868 | 0.78 | CRHR1 (0.35) | CA1CA2CYP3A4CA9CA12 | |
| SCHEMBL9348386 | 0.74 | ALDH1A1 (0.41) | CYP3A4MAPTPTGS2L3MBTL1TSHR | |
| SCHEMBL2059076 | 0.74 | HTR2A (0.43) | CA1CA2MAPTHTR2ACA9 | |
| SCHEMBL20380203 | 0.69 | HSD17B10 (0.47) | CA1CA2MAPTCA9CA12 | |
| SCHEMBL12383437 | 0.68 | IDO1 (0.38) | MAPTHTR2ATSHRHTT | |
| SCHEMBL28870388 | 0.68 | CA2 (0.67) | CA1CA2CA4CA6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |