Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524115 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9352610 | 0.81 | CTSV (0.48) | ALDH1A1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL10790436 | 0.80 | TUBB4A (0.49) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9352152 | 0.80 | MAPT (0.41) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9348560 | 0.79 | PKM (0.48) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9348473 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9348382 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL9349736 | 0.74 | CYP3A4 (0.37) | ALDH1A1CYP3A4MAPTTUBB4ATUBB | |
| SCHEMBL9348570 | 0.74 | CYP3A4 (0.37) | KDM4ECYP3A4MAPTTUBB4ATUBB | |
| SCHEMBL9348493 | 0.74 | CA1 (0.38) | CYP3A4MAPTTUBB1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |