Dimethylamine

Dimethylamine

SCHEMBL9350461

CNC.c1ccc(-c2nnc(-c3ccccc3)o2)cc1

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 15/20 0.81
NPC1 O15118 14/20 0.81
SMN1; SMN2 Q16637 10/20 0.81
HPGD P15428 9/20 0.69
NFKB1 P19838 3/20 0.69
NFKB2 Q00653 3/20 0.69
RELA Q04206 3/20 0.69
POLB P06746 1/20 0.69
ATAD2 Q6PL18 1/20 0.65
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
TSHR P16473 5/20 0.62
ALDH1A1 P00352 5/20 0.62
KDM4E B2RXH2 4/20 0.61
HSD17B10 Q99714 2/20 0.61
MAPT P10636 2/20 0.61
GLA P06280 1/20 0.61
ALOX15 P16050 1/20 0.61
NOTUM Q6P988 2/20 0.59
TP53 P04637 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46426 0.90 NPC1 (1.00) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL4343181 0.87 NPC1 (0.94) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL522555 0.85 NPC1 (0.90) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL22858502 0.85 NPC1 (0.90) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL74999 0.85 NPC1 (0.90) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL46424 0.85 NPC1 (0.90) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL1105099 0.83 NPC1 (0.85) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL12765577 0.83 NPC1 (0.85) RAB9ANPC1SMN1; SMN2HPGDNFKB1
Diethylamine SCHEMBL8179179 0.83 NPC1 (0.68) RAB9ANPC1SMN1; SMN2HPGDNFKB1
SCHEMBL6676849 0.83 GSK3B (0.65) RAB9ANPC1SMN1; SMN2HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314100-B1 Alpha-type titanyl phthalocyanine composition, method for production thereof, and electrophotographic sensitive material using same MITA INDUSTRIAL CO LTD (JP) 1994-09-14 EP disclosed
US-5106536-A Containing metal-free phthalocyanine; stability MITA INDUSTRIAL CO., LTD. (JP) 1992-04-21 US disclosed
US-4971877-A α-type titanyl phthalocyanine composition, method for production thereof, and electrophotographic sensitive material using same MITA INDUSTRIAL CO., LTD. (JP) 1990-11-20 US disclosed
EP-0314100-A2 Alpha-type titanyl phthalocyanine composition, method for production thereof, and electrophotographic sensitive material using same MITA INDUSTRIAL CO. LTD. (JP) 1989-05-03 EP disclosed
US-4788119-A PHOTOSTABILITY WHEN REPEATEDLY COPIED CANON KABUSHIKI KAISHA (JP) 1988-11-29 US disclosed
US-4390611-A Electrophotographic photosensitive azo pigment containing members CANON KABUSHIKI KAISHA (JP) 1983-06-28 US disclosed