Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 5/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254167 | 0.82 | AXL (0.40) | AXLAMY1AMAPTKDM4ETP53 | |
| SCHEMBL29254178 | 0.77 | CA9 (0.47) | MCL1MAPTKDM4ETP53ALDH1A1 | |
| SCHEMBL9315216 | 0.77 | HPGD (0.60) | TDO2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL9315345 | 0.75 | ESR1 (0.41) | MCL1AXLMAPTKDM4EALDH1A1 | |
| SCHEMBL29254187 | 0.75 | KDM4E (0.41) | AXLMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL476670 | 0.74 | ITK (0.48) | MCL1AXLMAPTKDM4EALDH1A1 | |
| SCHEMBL4406397 | 0.73 | CNR2 (0.62) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4429156 | 0.73 | KDM4E (0.44) | AXLMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL29254170 | 0.72 | LMNA (0.50) | MAPTKDM4ETP53ALDH1A1LMNA | |
| SCHEMBL9315401 | 0.71 | ALDH1A1 (0.46) | MCL1AXLAMY1AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |