⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421183 | 0.81 | LMNA (0.31) | — | |
| SCHEMBL4630604 | 0.77 | — | — | |
| SCHEMBL633501 | 0.72 | ADRB2 (0.35) | — | |
| SCHEMBL9501702 | 0.69 | — | — | |
| SCHEMBL11765536 | 0.69 | SLC29A1 (0.30) | — | |
| SCHEMBL16423547 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL11526431 | 0.67 | RECQL (0.33) | — | |
| SCHEMBL21669402 | 0.65 | SLC29A1 (0.31) | — | |
| SCHEMBL1664547 | 0.65 | CYP1A2 (0.46) | — | |
| SCHEMBL8719022 | 0.64 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354510-B1 | Primer compositions | DOW CORNING (US) | 1994-09-14 | — | — | EP | disclosed |
| US-4961967-A | ORGANOSILICON COMPOUND, ALKOXYMETHYLTRIAZINE DERIVATIVES AND DEFUNCTIONAL AROMATIC COMPOUNDS | DOW CORNING CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| US-4231910-A | ALKOXYMETHYLTRIAZINE AND ALKOXYSILANE COMPOUND | DOW CORNING CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |