Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959110 | 0.99 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL8959115 | 0.89 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL8614257 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL11177661 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL6104972 | 0.83 | CYP3A4 (0.46) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL11170916 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL28023159 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2RECQLTDP1 | |
| SCHEMBL10961144 | 0.80 | THRB (0.52) | ALDH1A1CYP3A4CA2TDP1LMNA | |
| SCHEMBL8958816 | 0.80 | MMP2 (0.50) | CA2RECQLTDP1LMNATSHR | |
| SCHEMBL9351922 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931865-B1 | DETERGENT COMPOSITION | UNILEVER NV (NL) | 2016-08-24 | — | — | EP | claimed |
| EP-0402339-B1 | Improved process for the production of carbonate esters | MONSANTO CO (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5252770-A | Process for the production of carbonate esters | MONSANTO COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0402339-A1 | Improved process for the production of carbonate esters | MONSANTO COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |