Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351930 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL8959110 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL8614257 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL11177661 | 0.82 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL8958823 | 0.82 | MMP2 (0.50) | CYP3A4CA2TSHRMAPK1TDP1 | |
| SCHEMBL11170916 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL28023159 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL10508838 | 0.80 | GAA (0.55) | ALDH1A1CYP3A4CA2MAPK1ATM | |
| SCHEMBL10961144 | 0.79 | THRB (0.52) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL8958941 | 0.78 | MMP2 (0.47) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931865-B1 | DETERGENT COMPOSITION | UNILEVER NV (NL) | 2016-08-24 | — | — | EP | claimed |
| EP-2931865-A1 | DETERGENT COMPOSITION | Unilever N.V. (NL) | 2015-10-21 | — | — | EP | claimed |
| WO-2014090568-A1 | DETERGENT COMPOSITION | UNILEVER N.V. (NL) | 2014-06-19 | — | — | WO | claimed |
| EP-2931865-B1 | DETERGENT COMPOSITION | UNILEVER NV (NL) | 2016-08-24 | — | — | EP | disclosed |
| EP-2931865-A1 | DETERGENT COMPOSITION | Unilever N.V. (NL) | 2015-10-21 | — | — | EP | disclosed |
| CN-104822816-A | Detergent composition | UNILEVER NV | 2015-08-05 | — | — | CN | disclosed |
| WO-2014090568-A1 | DETERGENT COMPOSITION | UNILEVER N.V. (NL) | 2014-06-19 | — | — | WO | disclosed |
| EP-0202698-B2 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | AKZO NOBEL NV (NL) | 1996-01-24 | — | — | EP | disclosed |
| US-5043089-A | Bleach activators | AKZO N.V. (NL) | 1991-08-27 | — | — | US | disclosed |
| EP-0202698-B1 | P-SULPHOPHENYL ALKYL CARBONATES AND THEIR USE AS BLEACHING ACTIVATORS | Akzo Nobel N.V. (NL) | 1989-10-25 | — | — | EP | disclosed |
| EP-0202698-A1 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | Akzo Nobel N.V. (NL) | 1986-11-26 | — | — | EP | disclosed |