Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173722 | 0.83 | PTPRZ1 (0.48) | PTPRZ1ALDH1A1EPHX2NR1H4AOC3 | |
| SCHEMBL933964 | 0.82 | PTPRZ1 (0.75) | PTPRZ1EPHX2NR1H4MAPTATM | |
| SCHEMBL17887621 | 0.78 | MAPT (0.40) | PTPRZ1ALDH1A1EPHX2NR1H4AOC3 | |
| SCHEMBL15881788 | 0.78 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1 | |
| SCHEMBL19705353 | 0.77 | KMT2A (0.68) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5390715 | 0.76 | SRC (0.61) | ALDH1A1EPHX2 | |
| SCHEMBL13040220 | 0.76 | MTNR1A (0.53) | ALDH1A1EPHX2AOC3HTTSMN1; SMN2 | |
| SCHEMBL12300586 | 0.75 | CETP (0.41) | PTPRZ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL934551 | 0.75 | GLS (0.61) | ALDH1A1EPHX2HTTSMN1; SMN2MTNR1A | |
| SCHEMBL11547699 | 0.75 | FFAR4 (0.42) | PTPRZ1EPHX2NR1H4MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |