SCHEMBL9353231

SCHEMBL9353231

O=S(=O)(S)c1ccc(Cl)cc1.[KH]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
CYP3A4 P08684 1/20 0.59
MAPK1 P28482 1/20 0.59
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
CA12 O43570 3/20 0.54
CA3 P07451 3/20 0.54
CA4 P22748 3/20 0.54
CA6 P23280 3/20 0.54
CA5A P35218 3/20 0.54
CA7 P43166 3/20 0.54
CA9 Q16790 3/20 0.54
CA13 Q8N1Q1 3/20 0.54
CA14 Q9ULX7 3/20 0.54
CA5B Q9Y2D0 3/20 0.54
MMP2 P08253 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MMP1 P03956 1/20 0.48
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7536145 0.97 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL10953683 0.95 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL4328031 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL22742 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL2122579 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL9313173 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL9762603 0.75 ALDH1A1 (0.68) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL338460 0.74 GAA (0.59) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL6568407 0.74 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL6913648 0.74 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112007045-A Chiral control 波涛生命科学有限公司 2020-12-01 CN disclosed
CN-104661664-B Chiral control 波涛生命科学有限公司 2020-07-03 CN disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed