Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355929 | 0.77 | CHRM2 (0.43) | CHRM2CHRM3ADRA1A | |
| SCHEMBL17147302 | 0.67 | CHRM2 (0.78) | CHRM2CHRM3ADRA1AADRA1B | |
| SCHEMBL9356394 | 0.66 | CHRM2 (0.46) | CHRM2CHRM3ADRA1A | |
| SCHEMBL10514861 | 0.63 | ALDH1A1 (0.40) | — | |
| SCHEMBL6946137 | 0.62 | CHRM2 (0.31) | CHRM2CHRM3 | |
| SCHEMBL1043555 | 0.62 | CHRM2 (1.00) | CHRM2CHRM3ADRA1AADRA1B | |
| SCHEMBL26323770 | 0.62 | TSHR (0.37) | — | |
| Bromide SCHEMBL6649504 | 0.61 | CHRM2 (0.97) | CHRM2CHRM3ADRA1AADRA1B | |
| SCHEMBL5810929 | 0.61 | ALDH1A1 (0.42) | CHRM2CHRM3 | |
| SCHEMBL9359494 | 0.60 | TERT (0.37) | ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310321-B1 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1989002889-A1 | IMMUNOMODULATORY AZASPIRANES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0310321-A2 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |