Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 7/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581343 | 0.74 | HTR1A (0.50) | TERTHTR1ADRD2DRD3STAT3 | |
| SCHEMBL8295688 | 0.73 | CHRM2 (0.42) | HTR1AADRA1BDRD2DRD3HIF1A | |
| Hydrochloric Acid SCHEMBL9355945 | 0.72 | ALOX15 (0.54) | DRD2DRD3 | |
| SCHEMBL9356394 | 0.72 | CHRM2 (0.46) | TERTHTR1ADRD2DRD3STAT3 | |
| SCHEMBL7920522 | 0.71 | ALOX15 (0.46) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6950425 | 0.70 | ALOX15 (0.45) | DRD2DRD3 | |
| SCHEMBL9360103 | 0.70 | — | — | |
| SCHEMBL10426634 | 0.69 | TERT (0.52) | TERTHTR1ADRD2DRD3STAT3 | |
| SCHEMBL18463363 | 0.69 | HTR1A (0.52) | HTR1AADRA1BDRD2DRD3HIF1A | |
| SCHEMBL18771744 | 0.67 | DNM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310321-B1 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1989002889-A1 | IMMUNOMODULATORY AZASPIRANES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0310321-A2 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |