Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SYK | P43405 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | GALR2 | O43603 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | FBP1 | P09467 | 4/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357736 | 0.85 | VCP (0.64) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL9361866 | 0.82 | ALDH1A1 (0.61) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL9357876 | 0.81 | ALDH1A1 (0.60) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL7455580 | 0.81 | ALDH1A1 (0.60) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL8591188 | 0.81 | ALDH1A1 (0.60) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL807768 | 0.79 | VCP (1.00) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL793160 | 0.79 | VCP (1.00) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL29727003 | 0.79 | VCP (1.00) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL28863042 | 0.78 | VCP (0.97) | VCPALDH1A1LMNAMAPTSYK | |
| SCHEMBL4808158 | 0.78 | ALDH1A3 (0.61) | ALDH1A1LMNAMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999139-A | Aminonitrostyrene Compound; Including a Polarizer, an Optical Resonator an a Reflector | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-03-12 | — | — | US | claimed |
| EP-0326133-B1 | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH & TELEPHONE (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4999139-A | Aminonitrostyrene Compound; Including a Polarizer, an Optical Resonator an a Reflector | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4997595-A | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0326133-A2 | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1989-08-02 | — | — | EP | disclosed |