SCHEMBL7455580

SCHEMBL7455580

CCN(CC)c1ccc(C=C[N+](=O)[O-])cc1F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
MAPT P10636 4/20 0.60
LMNA P02545 3/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
VCP P55072 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 3/20 0.49
MITF O75030 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ALDH3A1 P30838 1/20 0.49
FBP1 P09467 9/20 0.49
EGFR P00533 2/20 0.45
ABL1 P00519 1/20 0.45
ABL2 P42684 1/20 0.45
TLR4 O00206 1/20 0.43
TLR2 O60603 1/20 0.43
GALR2 O43603 1/20 0.43
MAPK1 P28482 1/20 0.43
SYK P43405 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8591188 1.00 ALDH1A1 (0.60) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL9361866 0.84 ALDH1A1 (0.61) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL9357876 0.83 ALDH1A1 (0.60) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL9358104 0.81 VCP (0.65) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL19036688 0.77 ALDH1A3 (0.41) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL9798981 0.77 ALDH3A1 (0.56) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL7995434 0.77 ALDH1A3 (0.65) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL9357724 0.77 LMNA (0.52) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL9357736 0.77 VCP (0.64) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL793784 0.76 VCP (0.72) ALDH1A1MAPTLMNAVCPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6280884-B1 HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-08-28 US claimed
US-6402994-B1 NEW CHROMOPHORE IMPARTS PHOTOREFRACTIVITY TO POLYMERS WITHOUT ADVERSELY AFFECTING OTHER PROPERTIES; THERMALLY STABLE; FOR USE IN OPTICAL RECORDING MEDIA AND BIOLOGICAL IMAGING CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-06-11 US disclosed
US-6280884-B1 HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-08-28 US disclosed
US-6090332-A Process of changing the refractive index of a composite containing a polymer and a compound having large dipole moment and polarizability and applications thereof CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-18 US disclosed
US-5759725-A Photoconductors and electrophotographic photoreceptors containing amorphous fullerenes KABUSHIKI KAISHA TOSHIBA (JP) 1998-06-02 US disclosed
US-5361148-A Apparatus for photorefractive two beam coupling INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-11-01 US disclosed