SCHEMBL6567757

SCHEMBL6567757

C=CCN(CC=C)c1ccccc1N=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.37
PTPN1 P18031 1/20 0.35
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 2/20 0.34
POLB P06746 2/20 0.34
NPC1 O15118 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9358558 0.80 ALDH1A1 (0.41) C5AR1PTPN1ALDH1A1POLBNPC1
SCHEMBL8672113 0.80 ALDH1A1 (0.41) C5AR1PTPN1ALDH1A1POLBNPC1
SCHEMBL8066324 0.77 ALDH1A1 (0.40) C5AR1ALDH1A1POLBNPC1PKM
SCHEMBL756089 0.75 MAPT (0.38) ALDH1A1NPC1RAB9ALMNAHTT
SCHEMBL7296721 0.74 C5AR1 (0.37) C5AR1PTPN1ALOX5ALDH1A1POLB
SCHEMBL3631013 0.72 C5AR1 (0.38) C5AR1PTPN1ALOX5ALDH1A1POLB
SCHEMBL299734 0.72 KMT2A (0.44) C5AR1PTPN1ALOX5ALDH1A1POLB
SCHEMBL9715199 0.72 MEN1 (0.47) ALDH1A1NPC1RAB9AHTTMEN1
SCHEMBL13740946 0.72 ALDH3A1 (0.37) ALDH1A1DRD3ESR1
SCHEMBL10819024 0.71 HPGD (0.49) PTPN1ALDH1A1NPC1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310819-B1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2019-06-12 EP disclosed
US-10221255-B2 Composition for the immediate stopping of a free-radical polymerization BASF SE (DE) 2019-03-05 US disclosed
US-20180171035-A1 COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION BASF SE (DE) 2018-06-21 US disclosed
EP-3310819-A1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2018-04-25 EP disclosed
WO-2016202883-A1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2016-12-22 WO disclosed
EP-1025132-B1 METHOD AND SOLUTION FOR IMMEDIATE TERMINATION OF RADICAL POLYMERISATION BASF AG (DE) 2004-03-03 EP disclosed
US-6518374-B1 Inhibitor solution, containing at least 10% phenothiazine, from 5 to 10% p-methoxyphenol and at least 50% N-methylpyrrolidone BASF AKTIENGESELLSCHAFT (DE) 2003-02-11 US disclosed
US-6518452-B1 A method of stabilizing an ester of (meth)acrylic acid against free-radical polymerization, comprising: adding to said ester of (meth)acrylic acid a polymerization inhibitor which comprises at least one nitroxyl radical and/or at least BASF AKTIENGESELLSCHAFT (DE) 2003-02-11 US disclosed
EP-1177218-B1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AG (DE) 2002-12-11 EP disclosed
EP-1177218-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
US-H1957-H1 ADDING A PHENOTHIAZINE-CONTAINING SOLUTION WHOSE SOLVENT COMPRISES AT LEAST 50% OF ITS WEIGHT OF AN N-ALKYLPYRROLIDONE BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
WO-2000064947-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10221255-B2 Composition for the immediate stopping of a free-radical polymerization FASTKD5, TYK2, FASTKD1 C5AR1 4561/4885PTPN1 781/4885ALOX5 258/4885
US-20180171035-A1 COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION FASTKD5, TYK2, FASTKD1 C5AR1 4561/4885PTPN1 781/4885ALOX5 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.