Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215923 | 0.83 | GABRA1 (0.59) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL9404582 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL10749042 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL4149652 | 0.76 | GABRA1 (0.59) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL4045452 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL9877225 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1HSD17B10LMNA | |
| SCHEMBL8517508 | 0.74 | GABRA1 (0.47) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL7852200 | 0.74 | GABRA1 (0.47) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL1420217 | 0.74 | GABRA1 (0.47) | GABRA1GABRB2KDM4EPOLBKMT2A | |
| SCHEMBL2461750 | 0.74 | XDH (0.48) | GABRA1GABRB2KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386905-B1 | Method of bonding vulcanisable elastomer compositions to metals | SUMITOMO RUBBER IND (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4990671-A | Method for making aminophenols and their amide derivatives | MALLINCKRODT, INC. (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0386905-A2 | Method of bonding vulcanisable elastomer compositions to metals | SUMITOMO RUBBER INDUSTRIES LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |