Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359013 | 0.87 | ELANE (0.39) | TDP1ALDH1A1LMNAELANEKMT2A | |
| SCHEMBL9402776 | 0.86 | KDM4E (0.47) | TDP1ALDH1A1LMNAELANEKMT2A | |
| SCHEMBL9402882 | 0.83 | MAPT (0.43) | TDP1ALDH1A1LMNAELANEKMT2A | |
| SCHEMBL9402620 | 0.82 | MAPT (0.46) | ALDH1A1ELANEKMT2AMEN1MAPT | |
| SCHEMBL9402700 | 0.82 | MAPT (0.50) | ALDH1A1LMNAELANEKMT2AMEN1 | |
| SCHEMBL9184350 | 0.81 | MAPT (0.44) | ALDH1A1MAPTRAB9ACA1CA2 | |
| SCHEMBL9402740 | 0.79 | MAPK14 (0.40) | ELANE | |
| SCHEMBL9402614 | 0.79 | CYP1A2 (0.41) | ALDH1A1LMNAMAPTRAB9ACA1 | |
| SCHEMBL9402779 | 0.77 | CYP1A2 (0.39) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL9402644 | 0.76 | ELANE (0.41) | TDP1ALDH1A1LMNAELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |