Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402614 | 0.91 | CYP1A2 (0.41) | CYP1A2CYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL9359013 | 0.87 | ELANE (0.39) | CYP1A2CYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL9402776 | 0.83 | KDM4E (0.47) | CYP1A2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9402882 | 0.78 | MAPT (0.43) | CYP1A2CYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL9184350 | 0.77 | MAPT (0.44) | KDM4EALDH1A1MAPTGAARAB9A | |
| SCHEMBL9402700 | 0.77 | MAPT (0.50) | CYP1A2CYP2C9ALDH1A1MAPTHPGD | |
| SCHEMBL9402620 | 0.77 | MAPT (0.46) | CYP1A2CYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL9402745 | 0.77 | TDP1 (0.44) | ALDH1A1MAPTATMRAB9AMEN1 | |
| SCHEMBL9402795 | 0.75 | TDP1 (0.39) | CYP2C9KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9402780 | 0.75 | ALDH1A1 (0.41) | CYP1A2CYP2C9ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |