Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359013 | 0.91 | ELANE (0.39) | MAPTALDH1A1HPGDLMNATDP1 | |
| SCHEMBL9402700 | 0.88 | MAPT (0.50) | MAPTALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL9402620 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4ECYP3A4ELANE | |
| SCHEMBL9402776 | 0.84 | KDM4E (0.47) | MAPTALDH1A1HPGDLMNATDP1 | |
| SCHEMBL9402745 | 0.83 | TDP1 (0.44) | MAPTALDH1A1LMNATDP1ELANE | |
| SCHEMBL9402614 | 0.80 | CYP1A2 (0.41) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL9402942 | 0.78 | ELANE (0.41) | MAPTALDH1A1HPGDLMNATDP1 | |
| SCHEMBL9402901 | 0.78 | ELANE (0.36) | MAPTALDH1A1HPGDLMNATDP1 | |
| SCHEMBL9402779 | 0.78 | CYP1A2 (0.39) | MAPTALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL9402740 | 0.77 | MAPK14 (0.40) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |