Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359013 | 0.89 | ELANE (0.39) | MAPTHTTNPSR1NPC1CYP2C9 | |
| SCHEMBL9402882 | 0.88 | MAPT (0.43) | MAPTHTTNPSR1NPC1CYP2C9 | |
| SCHEMBL9402620 | 0.85 | MAPT (0.46) | MAPTNPSR1CYP2C9ALDH1A1POLB | |
| SCHEMBL9402776 | 0.83 | KDM4E (0.47) | MAPTHTTALDH1A1CYP1A2LMNA | |
| SCHEMBL9402745 | 0.82 | TDP1 (0.44) | MAPTNPSR1ALDH1A1LMNAMEN1 | |
| SCHEMBL9402942 | 0.80 | ELANE (0.41) | MAPTHTTNPSR1NPC1CYP2C9 | |
| SCHEMBL9402614 | 0.79 | CYP1A2 (0.41) | MAPTCYP2C9ALDH1A1CYP1A2LMNA | |
| SCHEMBL9402901 | 0.77 | ELANE (0.36) | MAPTHTTNPC1ALDH1A1LMNA | |
| SCHEMBL9402779 | 0.77 | CYP1A2 (0.39) | MAPTHTTNPC1CYP2C9ALDH1A1 | |
| SCHEMBL9402740 | 0.76 | MAPK14 (0.40) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |