Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402779 | 0.91 | CYP1A2 (0.39) | CYP1A2CYP2C9KDM4EMAPTALDH1A1 | |
| SCHEMBL9359013 | 0.90 | ELANE (0.39) | CYP1A2CYP2C9KDM4EMAPTALDH1A1 | |
| SCHEMBL9402776 | 0.86 | KDM4E (0.47) | CYP1A2KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL9402882 | 0.80 | MAPT (0.43) | CYP1A2CYP2C9KDM4EMAPTALDH1A1 | |
| SCHEMBL9184350 | 0.80 | MAPT (0.44) | KDM4EMAPTALDH1A1GAAHDAC1 | |
| SCHEMBL9402620 | 0.79 | MAPT (0.46) | CYP1A2CYP2C9KDM4EMAPTALDH1A1 | |
| SCHEMBL9402700 | 0.79 | MAPT (0.50) | CYP1A2CYP2C9MAPTALDH1A1HPGD | |
| SCHEMBL9402745 | 0.79 | TDP1 (0.44) | MAPTALDH1A1ATMCA1CA2 | |
| SCHEMBL9402795 | 0.77 | TDP1 (0.39) | CYP2C9KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL9402780 | 0.77 | ALDH1A1 (0.41) | CYP1A2CYP2C9ALDH1A1HDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |