Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24497449 | 0.94 | ALDH1A1 (0.50) | ALDH1A1EPHX2NR1H4CYP2A6ALDH5A1 | |
| SCHEMBL3676731 | 0.85 | ALDH1A1 (0.54) | ALDH1A1EPHX2NR1H4CYP2A6ALDH5A1 | |
| SCHEMBL17148386 | 0.84 | MAPT (0.44) | ALDH1A1HSD17B10PGRARMEN1 | |
| SCHEMBL24482502 | 0.84 | PGR (0.40) | ALDH1A1HSD17B10PGRARMEN1 | |
| SCHEMBL10031827 | 0.83 | PGR (0.47) | ALDH1A1PGRARSMN1; SMN2CA2 | |
| SCHEMBL10001141 | 0.81 | ALDH1A1 (0.46) | ALDH1A1PGRARMEN1MITF | |
| SCHEMBL13268125 | 0.80 | ALDH1A1 (0.48) | ALDH1A1EPHX2NR1H4CYP2A6ALDH5A1 | |
| SCHEMBL13268123 | 0.79 | ALDH1A1 (0.47) | ALDH1A1EPHX2NR1H4CYP2A6ALDH5A1 | |
| SCHEMBL7235139 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALDH5A1ABATPARP10PARP3 | |
| SCHEMBL24471647 | 0.78 | KMT2A (0.42) | ALDH1A1KDM4EPGRARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | claimed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | claimed |
| JP-4230255-A | — | — | None | — | — | JP | disclosed |
| US-10294213-B2 | Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold | The Florida State University Research Foundation, Inc. (US) | 2019-05-21 | — | — | US | disclosed |
| US-20170168042-A1 | CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD | The Florida State University Research Foundation, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170168042-A1 | CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD | The Florida State University Research Foundation, Inc. | 2017-06-15 | — | — | US | disclosed |
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
| JP-H04230255-A | N-OXYIMIDO ACID DERIVATIVE | SANDOZ AG | 1992-08-19 | — | — | JP | disclosed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170168042-A1 | CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD | CLTA, ALAD, PELP1 | ALDH1A1 1706/4885EPHX2 4384/4885NR1H4 4269/4885 |
| US-10294213-B2 | Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold | CLTA, ALAD, PELP1 | ALDH1A1 1706/4885EPHX2 4384/4885NR1H4 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.