SCHEMBL24497449

SCHEMBL24497449

CC(C)(C)C(=O)c1ccc(-c2ccc(C=O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
PGR P06401 1/20 0.43
AR P10275 1/20 0.43
EPHX2 P34913 1/20 0.43
NR1H4 Q96RI1 1/20 0.43
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
PARP10 Q53GL7 1/20 0.41
PARP3 Q9Y6F1 1/20 0.41
CYP2A6 P11509 3/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
KIF11 P52732 1/20 0.39
DRD1 P21728 2/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359052 0.94 ALDH1A1 (0.56) ALDH1A1PGRAREPHX2NR1H4
SCHEMBL15745797 0.85 PGR (0.51) PGRARRXRARXRBRXRG
SCHEMBL3676731 0.80 ALDH1A1 (0.54) ALDH1A1EPHX2NR1H4PARP10PARP3
SCHEMBL24482502 0.79 PGR (0.40) ALDH1A1PGRARMEN1MITF
SCHEMBL17148386 0.79 MAPT (0.44) ALDH1A1PGRARMEN1MITF
SCHEMBL10031827 0.78 PGR (0.47) ALDH1A1PGRARSMN1; SMN2
SCHEMBL13246736 0.78 CA2 (0.52) ALDH1A1PGRARKIF11RXRA
SCHEMBL20630801 0.78 HSD17B1 (0.59) PGRARDRD1TYRKDM4E
SCHEMBL15746996 0.78 HSD17B1 (0.59) PGRARKIF11MMP2MMP9
SCHEMBL8237871 0.78 SMN1; SMN2 (0.59) ALDH1A1PGRARRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022263572-A1 COMPOSITE FILMS FOR MOBILE ELECTRONIC DEVICE COMPONENTS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-12-22 WO disclosed
WO-2022117519-A1 LIQUID CRYSTALLINE POLYESTERS (LCP) AND THERMOPLASTIC COMPOSITIONS HAVING LOW DIELECTRIC CONSTANT (DK) AND DISSIPATION FACTOR (DF) SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-09 WO disclosed