Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363416 | 0.87 | TACR1 (0.54) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL9359119 | 0.87 | PKM (0.56) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL9358982 | 0.87 | PKM (0.47) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL9363075 | 0.83 | FPR2 (0.53) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL9363425 | 0.83 | KDR (0.51) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL7642011 | 0.78 | HTT (0.45) | HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9359046 | 0.76 | MAPT (0.41) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL9358808 | 0.71 | KDR (0.47) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL9358719 | 0.70 | LMNA (0.50) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL6634344 | 0.70 | ROCK2 (0.41) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421456-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5223513-A | Anticholesterol agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0421456-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |