Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363075 | 0.94 | FPR2 (0.53) | PKMFPR2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9363416 | 0.92 | TACR1 (0.54) | PKMFPR2SMN1; SMN2TACR1MAPT | |
| SCHEMBL9359119 | 0.92 | PKM (0.56) | PKMFPR2L3MBTL1SMN1; SMN2TACR1 | |
| SCHEMBL9363425 | 0.88 | KDR (0.51) | PKMFPR2MAPTMEN1KMT2A | |
| SCHEMBL9359288 | 0.87 | DDX3X (0.49) | PKMSMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL7642011 | 0.85 | HTT (0.45) | SMN1; SMN2RAB9A | |
| SCHEMBL9359046 | 0.84 | MAPT (0.41) | FPR2SMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL9358730 | 0.80 | LMNA (0.44) | L3MBTL1TACR1POLBMEN1KMT2A | |
| SCHEMBL9358719 | 0.77 | LMNA (0.50) | PKMTACR1MAPTPOLBMEN1 | |
| SCHEMBL6634344 | 0.77 | ROCK2 (0.41) | MAPTLMNAWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421456-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5223513-A | Anticholesterol agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0421456-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |