Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442929 | 0.88 | CA2 (0.53) | CA2CA1TSHRTDP1CYP3A4 | |
| SCHEMBL296220 | 0.85 | CA2 (0.63) | CA2CA1TSHRTDP1CYP3A4 | |
| SCHEMBL14640944 | 0.85 | CA2 (0.63) | CA2CA1TSHRTDP1CYP3A4 | |
| SCHEMBL11242735 | 0.84 | PAM (0.61) | TSHRTDP1PAMP2RY10GPR34 | |
| SCHEMBL13123718 | 0.82 | EGLN1 (0.35) | CA2CA1MAPK1PAMP2RY10 | |
| SCHEMBL5675550 | 0.82 | CYP3A4 (0.59) | CA2CA1TSHRTDP1CYP3A4 | |
| SCHEMBL4211949 | 0.82 | TSHR (0.48) | TSHRTDP1PAMAKR1B1PPARG | |
| SCHEMBL28779815 | 0.79 | PAM (0.54) | TSHRTDP1PAMP2RY10GPR34 | |
| Stearic Acid SCHEMBL28535219 | 0.78 | GPR84 (0.52) | CA2CA1TSHRTDP1PAM | |
| SCHEMBL855142 | 0.78 | DGKA (0.61) | TSHRTDP1CYP3A4ATMPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6009978-A | — | — | None | — | — | JP | disclosed |
| JP-H069978-A | COMPOSITION FOR REFRIGERATING MACHINE WORKING FLUID | KAO CORP | 1994-01-18 | — | — | JP | disclosed |