Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633608 | 0.93 | BRD4 (0.34) | BRD4EGLN1POLBMAPTLMNA | |
| Hydrochloric Acid SCHEMBL3136757 | 0.91 | BRD4 (0.33) | BRD4EGLN1POLBMAPTLMNA | |
| SCHEMBL9360833 | 0.90 | RORC (0.32) | BRAFRORC | |
| SCHEMBL9438281 | 0.85 | MEN1 (0.34) | EGLN1KMT2ABRAFMMP13RORC | |
| SCHEMBL7131959 | 0.85 | BRD4 (0.36) | BRD4EGLN1MAPTLMNAMAPK1 | |
| SCHEMBL9360081 | 0.83 | MMP13 (0.36) | BRD4EGLN1LMNAMAPK1KMT2A | |
| SCHEMBL9359791 | 0.82 | CDK1 (0.32) | EGLN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL785277 | 0.81 | LMNA (0.33) | POLBMAPTLMNAMAPK1HTT | |
| SCHEMBL28567301 | 0.78 | CAMKK2 (0.42) | EGLN1POLBLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5972535 | 0.77 | MEN1 (0.36) | MAPTLMNATP53MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346670-A | Phthalocyanine and tetrabenztriazaporphyrin reagents | BRITISH TECHNOLOGY GROUP U.S.A. INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5135717-A | Imaging therapy | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1992-08-04 | — | — | US | disclosed |